We report on an intensive campaign of ground-based observations of Jupiter to support the Juno mission. Observations from the Very Large Telescope, NASA’s Infrared Telescope Facility, Subaru telescope and Hubble Space Telescope are used to determine Jupiter’s atmospheric state on the eve of Juno’s arrival (July 2016). We detect global asymmetries in temperature and composition as part of long-term atmospheric cycles, and discuss the thermal, chemical and aerosol changes associated with periodic upheavals to the typical banded structure. These observations will provide the spatial and temporal context to understand Juno's close-in studies of the giant planet's dynamic atmosphere.